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What are the symptoms of neuroblastoma?

The symptoms of neuroblastoma vary because the location of the tumor determines the symptoms that are noticed by the parents. The first symptoms are usually abdominal pain, swelling, and feelings of fullness caused by the pressure of the tumor. If the cancer has spread to the bone, the child may also feel bone pain. If the cancer has spread to the bone marrow, the child can become anemic, due to low red blood cells; may get sick easily because of a low red blood cell count; or may bruise easily because of reduced platelets. Neuroblastoma that has spread to the eye area causes protruding eyes and darkened skin around the eyes. Neuroblastoma can also spread to the skin, producing small bumps, or nodules, and to the spinal cord, which can cause weakness in the arms or legs and even paralysis. In rare cases, symptoms can include sudden, uncontrollable eye movements; poor coordination; sudden muscle spasms and contractions that result in jerky movements; and watery diarrhea.

More information on neuroblastoma

What is neuroblastoma? - Neuroblastoma is a malignant tumor derived from primitive neural crest cells. Neuroblastoma is a very common tumor of childhood.
What causes neuroblastoma? - The causes of neuroblastoma are not precisely known. Most neuroblastoma cells have genetic abnormalities involving chromosome #1.
What are the symptoms of neuroblastoma? - The symptoms of neuroblastoma vary because the location of the tumor determines the symptoms that are noticed by the parents.
How is neuroblastoma diagnosed? - A staging system has been developed for neuroblastoma to help the physician determine the best treatment for the disease.
What're treatments for neuroblastoma? - Surgery is used whenever possible, to remove as much of neuroblastoma as possible, and can generally cure the disease if the cancer. 
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Topics in endocrine disorders

Adrenal insufficiency
Addison's disease
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Conn's syndrome
Cushing's syndrome
Nelson's syndrome
Pheochromocytoma
Bartter's syndrome
Neuroblastoma
Adrenocortical carcinoma
Hypoglycemia
Insulinoma
Rickets
Osteomalacia
Hyperparathyroidism
Hypoparathyroidism
Pituitary gland disorders
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